Denaturing HPLC (dHPLC) system provides high sensitivity for DNA separations based on accurate temperature setting and precise gradient pump control. The modular system includes binary gradient, dHPLC colum, digital column heater, injector/autosampler, UV/Fluorescence detector and a 21bit data acquisition system. primary application is in clinical research and diagnostics from DNA fragment analysis to detection of somatic mutations as well as screening of inherited mutations and single- nucleotide polymorphisms (SNP).

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